nACh subunit d

Click on sections of picture to learn more about research on individual amino acids. Numbering of the nACh e subunit sequences start at the beginning of the mature protein. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M3-M4 Linker M4

nACh d -- GENBANK

nACh d -- FASTA

nACh d -- Alignment

 

 

 

 

 

 

 

 

 

N-Terminus

Leu 1 Lys 19 Glu 20 Leu 21 Arg 22 Pro 23 Val 24 Ala 25 His 26 Lys 27 Glu 28 Glu 29 Ser 30 Val 31 Asp 32 Val 33 Ala 34 Leu 35 Ala 36 Leu 37 Thr 38 Leu 39 Ser 40 Asn 41 Leu 42 Ile 43 Ser 44 leu 45 Lys 46 Glu 47 Val 48 Glu 49 Glu 50 Thr 51 Leu 52 Thr 53 Thr 54 Asn 55 Val 56 Trp 57 Ile 58 Glu 59 His 60 Gly 61 Trp 62 Thr 63 Asp 64 Asn 65 Arg 66 Leu 67 Lys 68 Trp 69 Asn 70 Ala 71 Glu 72 Glu 73 Phe 74 Gly 75 Asn 76 Ile 77 Ser 78 Val 79 Leu 80 Arg 81 Leu 82 Pro 83 Pro 84 Asp 85 Met 86 Val 87 Trp 88 Leu 89 Pro 90 Glu 91 Ile 92 Vla 93 Leu 94 Glu 95 Asn 96 Asn 97 Asn 98 Asp 99 Gly 100 Ser 101 Phe 102 Gln 103 Ile 104 Ser 105 Tyr 106 Ser 107 Cys 108 Asn 109 Val 110 Leu 111 Val 112 Tyr 113 His 114 Tyr 115 Gly 116 Phe 117 Val 118 Tyr 119 Trp 120 Leu 121 Pro 122 Pro 123 Ala 124 Ile 125 Phe 126 Arg 127 Ser 128 Ser 129 Cys 130 Pro 131 Ile 132 Ser 133 Val 134 Thr 135 Tyr 136 Phe 137 Pro 138 Phe 139 Asp 140 Trp 141 Gln 142 Asn 143 Cys 144 Ser 145 Leu 146 Lys 147 Phe 148 Ser 149 Ser 150 Leu 151 Lys 152 Tyr 153 Thr 154 Ala 155 Lys 156 Glu 157 Ile 158 Thr 159 Leu 160 Ser 161 Leu 162 Lys 163 Gln 164 Asp 165 Ala 166 Lys 167 Glu 168 Asn 169 Arg 170 Thr 171 Tyr 172 Pro 173 Val 174 Glu 175 Trp 176 Ile 177 Ile 178 Ile 179 Asp 180 Pro 181 Glu 182 Gly 183 Phe 184 Thr 185 Glu 186 Asn 187 Gly 188 Glu 189 Trp 190 Glu 191 Ile 192 Val 193 His 194 Arg 195 Pro 196 Ala 197 Arg 198 Val 199 Asn 200 Val 201 Asp 202 Pro 203 Arg 204 Ala 205 Pro 206 Leu 207 Asp 208 Ser 209 Pro 210 Ser 211 Arg 212 Gln 213 Asp 214 Ile 215 Thr 216 Phe 217 Tyr 218 Leu 219 Ile 220 Ile 221 Arg 222 Arg 223 Lys 224 Pro 225 Asn 18 Tyr 17 Gly 16 Lys 14 Glu 14 GLn 13 Phe 12 Leu 11 His 10 Arg 9 Ile 8 Leu 7 Arg 6 Glu 5 Glu 4 Glu 3 Asn 2
Residues with mutations: [ Glu 59 ] [ Val 134 ]

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M1

Tyr 248 Phe 247 Val 246 Leu 245 Asn 244 Val 243 Met 242 Phe 241 Ser 240 Ile 239 Leu 238 Val 237 Cys 236 Pro 235 Val 234 Leu 233 Ile 232 Asn 231 Ile 230 Ile 229 Tyr 228 Phe 227 Leu 226

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M1-M2 Linker

Leu 249 Pro 250 Ala 251 Asp 252 Ser 253 Gly 254 Glu 255 Lys 256

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M2

Tyr 257 Ser 258 Val 259 Ala 260 Ile 261 Ser 262 Val 263 Leu 264 Leu 265 Ala 266 Gln 267 Ser 268 Val 269 Phe 270 Leu 271 Leu 272 Leu 273 Ile 274 Ser 275

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M2-M3 Linker

Lys 276 Arg 277 Leu 278 Pro 279 Ala 280 Thr 281 Ser 282 Met 283 Ala 284 Ile 285

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M3

Pro 286 Leu 287 Ile 288 Gly 289 Lys 290 Phe 291 Leu 292 Leu 293 Phe 294 Gly 295 Met 296 Val 297 Leu 298 Val 299 Thr 300 Met 301 Val 302 Val 303 Val 304

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M3-M4 Linker

Arg 439 Met 438 His 437 Asp 436 Ala 435 Ile 434 Phe 433 Arg 432 Val 431 Gly 430 Arg 439 Met 438 His 437 Asp 436 Ala 435 Ile 434 Phe 433 Arg 432 Val 431 Gly 430 Arg 439 Met 438 His 437 Asp 436 Ala 435 Ile 434 Phe 433 Arg 432 Val 431 Gly 430 Arg 429 Met 428 His 427 Asn 426 Val 425 Ile 424 Phe 423 Asn 422 Ala 421 Gly 420 Asp 419 Val 418 Ala 417 Pro 416 Lys 415 Leu 414 Glu 413 Asn 412 Phe 411 Leu 410 Glu 409 Gln 408 Gln 407 Arg 406 Gln 405 Glu 404 Ser 403 Ser 402 Ala 401 Pro 400 Pro 399 Arg 398 Arg 397 Ala 396 Thr 395 Thr 394 Leu 393 Arg 392 Arg 391 Ala 390 Leu 389 Gly 388 His 387 Arg 386 Glu 385 Ser 384 Gln 383 Lys 382 Glu 381 Phe 380 Met 379 Leu 378 Asp 377 Ser 376 Arg 375 Ser 374 Lys 373 Leu 372 Leu 371 Phe 370 Tyr 369 Glu 368 Glu 367 Ala 366 Lys 365 Ser 364 Ile 363 Tyr 362 Gly 361 Leu 360 Ser 359 Ser 358 Ser 357 Arg 356 Arg 355 Val 354 Leu 353 Ala 352 Gly 351 Pro 350 Ser 349 Pro 348 Gly 347 Asp 346 Glu 345 Ala 344 Pro 343 Arg 342 Ser 341 Met 340 His 339 Leu 338 Leu 337 Glu 336 Pro 335 Leu 334 Thr 333 Glu 332 Leu 331 Phe 330 Leu 329 Lys 328 Lys 327 Val 326 Gly 325 Glu 324 Ser 323 Leu 322 Val 321 His 320 Thr 319 Ser 318 Pro 317 Thr 316 Arg 315 Phe 314 His 313 Ile 312 Asn 311 Leu 310 Val 309 Ile 308 Val 307 Cys 306 Ile 305

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M4

Val 455 Val 456 Thr 457 Pro 458 Val 459 Met 460 Val 461 Val 462 Gly 463 Thr 464 Ala 465 Trp 466 Ile 467 Phe 468 Leu 469 Gln 470 Gly 471 Val 472 Tyr 473 Asn 474 Gln 475 Pro 476 Pro 477 Pro 478 Gln 479 Pro 480 Phe 481 Pro 482 Gly 483 Asp 484 Pro 485 486 Tyr 487 Ser 488 Tyr 489 Asn 490 Val 491 Gln 492 Asp 493 Lys 494 Arg 495 Phe 496 Ile

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Alignment

N-Terminus First Membrane Spanning Second Membrane Spanning Third Membrane Spanning Outside the Cell Inside the Cell C-Terminus