nACh subunit a7

Click on sections of picture to learn more about research on individual amino acids. Numbering of the nACh a7 subunit sequences start at the beginning of the mature protein. Only amino acids in the mature protein are shown.


amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M3-M4 Linker M4

nACh a7 -- GENBANK

nACh a7 -- FASTA

nACh a7 -- Alignment

 

 

 

 

 

 


 

 

N-Terminus

Gly 1 Glu 2 Phe 3 Gln 4 Arg 5 Lys 6 Leu 7 Tyr 8 Lys 9 Glu 10 Leu 11 Val 12 Lys 13 Asn 14 Tyr 15 Asn 16 Pro 17 Leu 18 Glu 19 Arg 20 Pro 21 Val 22 Ala 23 Asn 24 Asp 25 Ser 26 Gln 27 Pro 28 Leu 29 Thr 30 Val 31 Tyr 32 Phe 33 Ser 34 Leu 35 Ser 36 Leu 37 Leu 38 Gln 39 Ile 40 Met 41 Asp 42 Val 43 Asp 44 Glu 45 Lys 46 Asn 47 Gln 48 Val 49 Leu 50 Thr 51 Thr 52 Asn 53 Ile 54 Trp 55 Leu 56 Gln 57 Met 58 Ser 59 Trp 60 Thr 61 Asp 62 His 63 Tyr 64 Leu 65 Gln 66 Trp 67 Asn 68 Val 69 Ser 70 Glu 71 Tyr 72 Pro 73 Gly 74 Val 75 Lys 76 Tyr 77 Val 78 Arg 79 Phe 80 Pro 81 Asp 82 Gly 83 Gln 84 Ile 85 Trp 86 Lys 87 Pro 88 Asp 89 Ile 90 Leu 91 Leu 92 Tyr 93 Asn 94 Ser 95 Ala 96 Asp 97 Glu 99 Arg 99 Phe 100 Asp 101 Ala 102 Thr 103 Phe 104 His 105 Thr 106 Asn 107 Val 108 Leu 109 Val 110 Asn 111 Ser 112 Ser 113 Gly 114 His 115 Cys 116 Gln 117 Tyr 118 Leu 119 Pro 120 Pro 121 Gly 122 Ile 123 Phe 124 Lys 125 Ser 126 Ser 127 Cys 128 Tyr 129 Ile 130 Asp 131 Val 132 Arg 133 Trp 134 Phe 135 Pro 136 Phe 137 Asp 138 Val 139 Gln 140 His 141 Cys 142 Lys 143 Leu 144 Lys 145 Phe 146 Gly 147 Ser 148 Trp 149 Ser 150 Tyr 151 Gly 152 Gly 153 Trp 154 Ser 155 Leu 156 Asp 157 Leu 158 Gln 159 Met 160 Gln 161 Glu 162 Ala 163 Asp 164 Ile 165 Ser 166 Gly 167 Tyr 168 Ile 169 Pro 170 Asn 171 Gly 172 Glu 173 Trp 174 Asp 175 Leu 176 Val 177 Gly 178 Ile 179 Pro 180 Gly 181 Lys 182 Arg 183 Ser 184 Glu 185 Arg 186 Phe 187 Tyr 188 Glu 189 Cys 190 Cys 191 Lys 192 Glu 193 Pro 194 Tyr 195 Pro 196 Asp 197 Val 198 Thr 199 Phe 200 Thr 201 Val 202 Thr 203 Met 204 Arg 205 Arg 206 Arg 207

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M1

Pro 233 Leu 232 Leu 231 Phe 230 Val 229 Leu 228 Leu 227 Ala 226 Leu 225 Ala 224 Ser 223 Ile 222 Leu 221 Val 220 Cys 219 Pro 218 Ile 217 Leu 216 Leu 215 Asn 214 Leu 213 Gly 212 Tyr 211 Tyr 210 Leu 209 Thr 208

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M1-M2 Linker

Ala 234 Asp 235 Ser 236 Gly 237 Glu 238 Lys 239

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M2

Ile 240 Ser 241 Leu 242 Gly 243 Ile 244 Thr 245 Val 246 Leu 247 Leu 248 Ser 249 Leu 250 Thr 251 Val 252 Phe 253 Met 254 Leu 255 Ile 256 Val 257 Ala 258 Glu 259 Ile 260 Met 261 Pro 262

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M2-M3 Linker

Ala 263 Thr 264 Ser 265 Asp 266 Ser 267 Val 268
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M3

Pro 269 Leu 270 Ile 271 Ala 272 Gln 273 Tyr 274 Phe 275 Ala 276 Ser 277 Thr 278 Met 279 Ile 280 Ile 281 Val 282 Gly 283 Leu 284 Ser 285 Val 286 Val 287 Val 288 Thr 289 Val 290 Ile 291 Val 292 Leu 293

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M3-M4 Linker

Arg 447 Asp 446 Val 445 Val 444 Cys 443 Ala 442 Ala 441 Phe 440 Lys 439 Trp 438 Glu 437 Ser 436 Cys 435 Val 434 Ala 433 Glu 432 Ser 431 Glu 430 Asp 429 Gln 428 Cys 427 Arg 426 Phe 425 Arg 424 Asn 423 Ala 422 Ile 421 Tyr 420 Arg 419 Val 418 Glu 417 Glu 416 Leu 415 Ile 414 Lys 413 Ala 412 Leu 411 Asp 410 Pro 409 Asp 408 Gly 407 Glu 406 Pro 405 Pro 404 Gln 403 Gly 402 Gly 401 His 400 Leu 399 Leu 398 His 397 Glu 396 Asp 395 Hal 394 Thr 393 Pro 392 Ser 391 Cys 380 Ala 389 Met 388 Arg 387 Gly 386 Cys 385 Val 384 Val 383 Gly 382 Ser 381 Asp 380 Pro 379 Thr 378 Phe 377 Val 376 Cys 375 His 374 Val 373 Gly 372 Asp 371 Leu 370 Gly 369 Arg 368 Phe 367 Gly 366 Ile 365 Tyr 364 Leu 363 Leu 362 Asn 361 Gly 360 Asn 359 Ser 358 Ala 357 Pro 356 Pro 355 Pro 354 Ala 353 Val 352 Ala 351 Ser 350 Met 349 Glu 348 Val 347 Ser 346 Ala 345 Leu 344 Ser 343 Cys 342 Arg 341 Arg 340 Gln 339 Lys 338 His 337 Gln 336 Cys 335 Ala 334 Pro 333 Arg 332 Val 331 Lys 330 Asp 329 Glu 328 Gly 327 Pro 326 Arg 325 Lys 324 Met 323 Arg 322 Leu 321 Phe 320 Trp 319 Ala 318 Cys 317 Trp 316 Asn 315 Leu 314 Leu 313 Ile 312 Val 311 Arg 310 Thr 309 Trp 308 Lys 307 Pro 306 Met 305 Lys 304 Gly 303 Gly 302 Asp 301 Pro 300 Asp 299 His 298 His 297 His 296 Tyr 295 Gln 294

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M4

Leu 448 Cys 449 Leu 450 Met 451 Ala 452 Phe 453 Ser 454 Val 455 Phe 456 Thr 457 Ile 458 Ile 459 Cys 460 Thr 461 Ile 462 Gly 463 Ile 464 Leu 465 Met 466 Ser 467 Ala 468 Pro 469 Asn 470 Phe 471 Val 472 Glu 473 Ala 474 Val 475 Ser 476 Phe 477 Asp 478 Phe 479 Ala 480

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Alignment

N-Terminus First Membrane Spanning Second Membrane Spanning Third Membrane Spanning Outside the Cell Inside the Cell C-Terminus