nACh subunit a6

Click on sections of picture to learn more about research on individual amino acids. Numbering of the nACh a5 subunit sequences starts at the end of the signal sequence. Only amino acids in the mature protein are shown.


amino acid all M3 M2 M1-M2 Linker M1 M2-M3 Linker N-Terminus M3-M4 Linker M4

nACh a6 -- GENBANK

nACh a6 -- FASTA

nACh a6 -- Alignment

 

 

 

 

 

 

 

 

 

N-Terminus

Cys 1 Ala 2 Thr 3 Glu 4 Glu 5 Arg 6 Leu 7 Phe 8 His 9 Lys 10 Leu 11 Phe 12 Ser 13 His 14 Tyr 15 Asn 16 Gln 17 Phe 18 Ile 19 Arg 20 Pro 21 Val 22 Glu 23 Asn 24 Val 25 Ser 26 Asp 27 Pro 28 Val 29 Thr 30 Val 31 His 32 Phe 33 Glu 34 Val 35 Ala 36 Ile 37 Thr 38 Gln 39 Leu 40 Ala 41 Asn 42 Val 43 Asp 44 Glu 45 Val 46 Asn 47 Gln 48 Ile 49 Met 50 Glu 51 Thr 52 Asn 53 Leu 54 Trp 55 Leu 56 Arg 57 His 58 Ile 59 Trp 60 Asn 61 Asp 62 Tyr 63 Lys 64 Leu 65 Arg 66 Trp 67 Asp 68 Pro 69 Met 70 Glu 71 Tyr 72 Asp 73 Gly 74 Ile 75 Glu 76 Thr 77 Leu 78 Arg 79 Val 80 Pro 81 Ala 82 Asp 83 Lys 84 Ile 85 Trp 86 Lys 87 Pro 88 Asp 89 Ile 90 Val 91 Leu 92 Tyr 93 Asn 94 Asn 95 Ala 96 Val 97 Gly 98 Asp 99 Phe 100 Gln 101 Val 102 Glu 103 Gly 104 Lys 105 Thr 106 Lys 107 Ala 108 Leu 109 Leu 110 Lys 111 Tyr 112 Asn 113 Gly 114 Met 115 Ile 116 Thr 117 Trp 118 Thr 119 Pro 120 Pro 121 Ala 122 Ile 123 Phe 124 Lys 125 Ser 126 Ser 127 Cys 128 Pro 129 Met 130 Asp 131 Ile 132 Thr 133 Phe 134 Phe 135 Pro 136 Phe 137 Asp 138 His 139 Gln 140 Asn 141 Cys 142 Ser 143 Leu 144 Lys 145 Phe 146 Gly 147 Ser 148 Trp 149 Thr 150 Tyr 151 Asp 152 Lys 153 Ala 154 Glu 155 Ile 156 Asp 157 Leu 158 Leu 159 Ile 160 Ile 161 Gly 162 Ser 163 Lys 164 Val 165 Asp 166 Met 167 Asn 168 Asp 169 Phe 170 Trp 171 Glu 172 Asn 173 Ser 174 Glu 175 Trp 176 Glu 177 Ile 178 Ile 179 Asp 180 Ala 181 Ser 182 Gly 183 Tyr 184 Lys 185 His 186 Asp 187 Ile 188 Lys 189 Tyr 190 Asn 191 Cys 192 Cys 193 Glu 194 Glu 195 Ile 196 Tyr 197 Thr 198 Asp 199 Ile 200 Thr 201 Tyr 202 Ser 203 Phe 204 Tyr 205 Ile 206 Arg 207 Arg 208 Leu 209

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M1

Pro 235 Leu 234 Tyr 233 Phe 232 Val 231 Leu 230 Val 229 Thr 228 Leu 227 Phe 226 Ser 225 Ile 224 Phe 223 Leu 222 Cys 221 Pro 220 Ile 219 Ile 218 Leu 217 Asn 216 Ile 215 Thr 214 Tyr 213 Phe 212 Met 211 Pro 210

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M1-M2 Linker

Ser 236 Asp 237 Cys 238 Gly 239 Glu 240 Lys 241

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M2

Val 242 Thr 243 Leu 244 Cys 245 Ile 246 Ser 247 Val 248 Leu 249 Leu 250 Ser 251 Leu 252 Thr 253 Val 254 Phe 255 Leu 256 Leu 257 Val 258 Ile 259 Thr 260 Glu 261 Thr 262 Ile 263 Pro 264

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M2-M3 Linker

Ser 265 Thr 266 Ser 267 Leu 268 Val 269 Val 270
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M3

Pro 271 Leu 272 Val 273 Gly 274 Glu 275 Tyr 276 Leu 277 Leu 278 Phe 279 Thr 280 Met 281 Ile 282 Phe 283 Val 284 Thr 285 Leu 286 Ser 287 Ile 288 Val 289 Val 290 Thr 291 Val 292 Phe 293 Val 294 Leu 295 Asn 296

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M3-M4 Linker

Arg 435 Asp 434 Val 433 Val 432 Met 431 Ala 430 Val 429 Tyr 428 Lys 427 Trp 426 Asp 425 Asp 424 Glu 423 Val 422 Glu 421 Lys 420 Thr 419 Glu 418 Asn 417 His 416 Ser 415 Lys 414 Met 413 Asn 412 Glu 411 Ala 410 Ile 409 Phe 408 Gln 407 Val 406 Ser 405 Asn 404 Ile 403 Val 402 Asp 401 Glu 400 Val 399 Glu 398 Pro 397 Ser 396 His 395 Glu 394 Ser 393 Asn 392 Glu 391 Val 390 Val 389 Trp 388 Gln 387 Leu 386 Pro 385 Gln 384 His 383 Ser 382 Leu 381 Arg 380 Arg 379 Lys 378 Ser 377 Thr 376 Ala 375 Leu 374 Glu 373 Asn 372 Ser 371 Lys 370 His 369 Cys 368 His 367 Phe 366 Cys 365 Glu 364 Lys 363 Leu 362 His 361 Arg 360 Pro 359 Glu 358 Gly 357 His 356 Ser 355 Ala 354 Leu 353 Lys 352 Glu 351 Lys 350 Ala 349 Pro 348 Arg 347 Arg 346 Ala 345 Leu 344 Gly 343 Arg 342 Pro 341 Val 340 Ala 339 Asp 338 Ser 337 Gly 336 Thr 335 Gly 334 Arg 333 Thr 332 Lys 331 Asp 330 Leu 329 Pro 328 Trp 327 Arg 326 Met 325 Leu 324 Leu 323 Val 322 Gln 321 Pro 320 Leu 319 Leu 318 Lys 317 Leu 316 Phe 315 Val 314 Thr 313 Lys 312 Val 311 Trp 310 Arg 309 Pro 308 Met 307 Thr 306 His 305 Thr 304 Thr 303 Pro 302 Thr 301 Arg 300 Tyr 299 His 298 Ile 297

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M4

Val 436 Phe 437 Leu 438 Trp 439 Val 440 Phe 441 Ile 442 Ile 443 Val 444 Cys 445 Val 446 Phe 447 Gly 448 Thr 449 Ala 450 Gly 451 Leu 452 Phe 453 Leu 454 Gln 455 Pro 456 Leu 457 Leu 458 Gly 459 Asn 460 Thr 461 Gly 462 Lys 463 Ser 464

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Alignment

N-Terminus First Membrane Spanning Second Membrane Spanning Third Membrane Spanning Outside the Cell Inside the Cell C-Terminus