nACh subunit a10

Click on sections of picture to learn more about research on individual amino acids. Numbering of the nACh a10 subunit sequences starts at the end of the signal sequence. Only amino acids in the mature protein are shown.


amino acid all M3 M2 M1-M2 Linker M1 M2-M3 Linker N-Terminus M3-M4 Linker M4

nACh a10 -- GENBANK

nACh a10 -- FASTA

nACh a10 -- Alignment

 

 

 

 

 

M2-M3 Linker M1 M1-M2 Linker M2 N-Terminus M3 M3-M4 Linker M4

 

 

 


 

 

 

 

 

N-Terminus

Ala 1 Glu 2 Gly 3 Arg 4 Leu 5 Ala 6 Leu 7 Lys 8 Leu 9 Phe 10 Arg 11 Asp 12 Leu 13 Phe 14 Ala 15 Asn 16 Tyr 17 Thr 18 Ser 19 Ala 20 Leu 21 Arg 22 Pro 23 Val 24 Ala 25 Asp 26 Thr 27 Asp 28 Gln 29 Thr 30 Leu 31 Asn 32 Val 33 Thr 34 Leu 35 Glu 36 Val 37 Thr 38 Leu 39 Ser 40 Gln 41 Ile 42 Ile 43 Asp 44 Met 45 Asp 46 Glu 47 Arg 48 Asn 49 Gln 50 Val 51 Leu 52 Thr 53 Leu 54 Tyr 55 Leu 56 Trp 57 Ile 58 Arg 59 Gln 60 Glu 61 Trp 62 Thr 63 Asp 64 Ala 65 Tyr 66 Leu 67 Arg 68 Trp 69 Asp 70 Pro 71 Asn 72 Ala 73 Tyr 74 Gly 75 Gly 76 Leu 77 Asp 78 Ala 79 Ile 80 Arg 81 Ile 82 Pro 83 Ser 84 Ser 85 Leu 86 Val 87 Trp 88 Arg 89 Pro 90 Asp 91 Ile 92 Val 93 Leu 94 Tyr 95 Asn 96 Lys 97 Ala 98 Asp 99 Ala 100 Gln 101 Pro 102 Pro 103 Gly 104 Ser 105 Ala 106 Ser 107 Thr 108 Asn 109 Val 110 Val 111 Leu 112 Arg 113 His 114 Asp 115 Gly 116 Ala 117 Val 118 Arg 119 Trp 120 Asp 121 Ala 122 Pro 123 Ala 124 Ile 125 Thr 126 Arg 127 Ser 128 Ser 129 Cys 130 Arg 131 Val 132 Asp 133 Val 134 Ala 135 Ala 136 Phe 137 Pro 138 Phe 139 Asp 140 Ala 141 Gln 142 His 143 Cys 144 Gly 145 Leu 146 Thr 147 Phe 148 Gly 149 Ser 150 Trp 151 Thr 152 His 153 Gly 154 Gly 155 His 156 Gln 157 Leu 158 Asp 159 Val 160 Arg 161 Pro 162 Arg 163 Gly 164 Ala 165 Ala 166 Ala 167 Ser 168 Leu 169 Ala 170 Asp 171 Phe 172 Val 173 Glu 174 Asn 175 Val 176 Glu 177 Trp 178 Arg 179 Val 180 Leu 181 Gly 182 Met 183 Pro 184 Ala 185 Arg 186 Arg 187 Arg 188 Val 189 Leu 190 Thr 191 Tyr 192 Gly 193 Cys 194 Cys 195 Ser 196 Glu 197 Pro 198 Tyr 199 Pro 200 Asp 201 Val 202 Thr 203 Phe 204 Thr 205 Leu 206 Leu 207 Leu 208 Arg 209 Arg 210 Arg 211 Ala 212 Ala 213 Ala 214

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M1

Asp 239 Ala 238 Pro 237 Leu 236 His 235 Phe 234 Ala 233 Leu 232 Pro 231 Ala 230 Leu 229 Leu 228 Ser 227 Ile 226 Leu 225 Val 224 Cys 223 Pro 222 Leu 221 Leu 220 Leu 219 Asn 218 Cys 217 Val 216 Tyr 215

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M1-M2 Linker

Ser 240 Gly 241 Glu 242 Lys 243 Val 244

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M2

Ser 245 Leu 246 Gly 247 Val 248 Thr 249 Val 250 Leu 251 Leu 252 Ala 253 Leu 254 Thr 255 Val 256 Phe 257 Gln 258 Leu 259 Leu 260 Leu 261 Ala 262 Glu 263 Ser 264 Met 265 Pro 266

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M2-M3 Linker

Pro 267 Ala 268 Glu 269 Ser 270 Val 271 Pro 272 Leu 273 Ile 274 Gly 275 Lys 276

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M3

Tyr 277 Tyr 278 Met 279 Ala 280 Thr 281 Met 282 Thr 283 Met 284 Val 285 Thr 286 Phe 287 Ser 288 Thr 289 Ala 290 Leu 291 Thr 292 Ile 293 Leu 294 Ile 295 Met 296 Asn 297 Leu 298 His 299

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M3-M4 Linker

Arg 404 Asp 403 Met 402 Val 401 Arg 400 Ala 399 Leu 398 Arg 397 Lys 396 Trp 395 Asp 394 Glu 393 His 392 Cys 391 Arg 390 Gln 389 Ala 388 Ala 387 Arg 386 His 385 Ser 384 Leu 383 Phe 382 Thr 381 Asn 380 Ala 379 Ile 378 Thr 377 Ala 376 Val 375 His 374 His 373 Leu 372 Leu 371 Ala 370 Glu 369 Gln 368 Arg 367 Cys 366 Leu 365 Cys 364 Arg 363 Pro 362 Glu 361 His 360 Cys 359 Pro 358 Gly 357 Ala 356 Pro 355 Pro 354 Gly 353 Ala 352 Gly 351 Gly 350 Glu 349 Pro 348 Ser 347 Gln 346 Pro 345 Ser 344 Pro 343 Ser 342 Leu 341 Glu 340 Pro 339 Pro 338 Arg 337 Ser 336 Gln 335 Gly 334 Cys 333 Pro 332 Glu 331 Gly 330 Arg 329 Glu 328 Arg 327 Val 326 Cys 325 Leu 324 Gly 323 Arg 322 Ala 321 Leu 320 His 319 Gly 318 Leu 317 Leu 316 Leu 315 Ala 314 Arg 313 Ala 312 Trp 311 Ala 310 Pro 309 Val 308 Pro 307 Arg 306 Val 305 Ser 304 Pro 303 Gly 302 Cys 301 Tyr 300

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M4

Phe 405 Phe 406 Leu 407 Ala 408 Ile 409 Phe 410 Phe 411 Ser 412 Met 413 Ala 414 Leu 415 Val 416 Met 417 Ser 418 Leu 419 Leu 420 Val 421 Leu 422 Val 423 Gln 424 Ala 425 Leu 426

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Alignment

N-Terminus First Membrane Spanning Second Membrane Spanning Third Membrane Spanning Outside the Cell Inside the Cell C-Terminus