nACh subunit b3

Click on sections of the picture to learn more about research on individual amino acids. Numbering of the nACh b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.


amino acid all M4 M3-M4 Linker M3 M1 M2 M1-M2 Linker N-Terminus M2-M3 Linker

 

 

nACh b3 -- GENBANK

nACh b3 -- FASTA

nACh b3 -- Alignment

 

 

 

 

 

 

 

 

 

N-Terminus

Leu 36 Phe 37 Gln 38 Gly 39 Tyr 40 Gln 41 Lys 42 Trp 43 Val 44 Arg 45 Pro 46 Val 47 Leu 48 His 49 Ser 50 Asn 51 Asp 52 Thr 53 Ile 54 Lys 55 Val 56 Tyr 57 Phe 58 Gly 59 Leu 60 Lys 61 Ile 62 Ser 63 Gln 64 Leu 65 Val 66 Asp 67 Val 68 Asp 69 Glu 70 Lys 71 Asn 72 Gln 73 Leu 74 Met 75 Thr 76 Thr 77 Asn 78 Val 79 Trp 80 Leu 81 Lys 82 Gln 83 Glu 84 Trp 85 Thr 86 Asp 87 His 88 Lys 89 Leu 90 Arg 91 Trp 92 Asn 93 Pro 94 Asp 95 Asp 96 Tyr 97 Gly 98 Gly 99 Ile 100 His 101 Ser 102 Ile 103 Lys 104 Val 105 Pro 106 Ser 107 Glu 108 Ser 109 Leu 110 Trp 111 Leu 112 Pro 113 Asp 114 Ile 115 Val 116 Leu 117 Phe 118 Glu 119 Asn 120 Ala 121 Asp 122 Gly 123 Arg 124 Phe 125 Glu 126 Gly 127 Ser 128 Leu 129 Met 130 Thr 131 Lys 132 Val 133 Ile 134 Val 135 Lys 136 Ser 137 Asn 138 Gly 139 Thr 140 Val 141 Val 142 Trp 143 Thr 144 Pro 145 Pro 146 Ala 147 Ser 148 Tyr 149 Lys 150 Ser 151 Ser 152 Cys 153 Thr 154 Met 155 Asp 156 Val 157 Thr 158 Phe 159 Phe 160 Pro 161 Phe 162 Asp 163 Arg 164 Gln 165 Asn 166 Cys 167 Ser 168 Met 169 Lys 170 Phe 171 Gly 172 Ser 173 Trp 174 Thr 175 Tyr 176 Asp 177 Gly 178 Thr 179 Met 180 Val 181 Asp 182 Leu 183 Ile 184 Leu 185 Ile 186 Asn 187 Glu 188 Asn 189 Val 190 Asp 191 Arg 192 Lys 193 Asp 194 Phe 195 Phe 196 Asp 197 Asn 198 Gly 199 Glu 200 Trp 201 Glu 202 Ile 203 Leu 204 Asn 205 Ala 206 Lys 207 Gly 208 Met 209 Lys 210 Gly 211 Asn 212 Arg 213 Arg 214 Asp 215 Gly 216 Val 217 Tyr 218 Ser 219 Tyr 220 Pro 221 Phe 222 Ile 223 Thr 224 Tyr 225 Ser 226 Phe 227 Val 228 Leu 229

Residues with mutations: [ ]

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M1

Pro 258 Leu 257 Tyr 256 Val 254 Leu 253 Phe 255 Leu 250 Thr 251 Val 252 Phe 249 Ser 248 Leu 247 Gly 246 Leu 245 Cys 244 Pro 243 Ile 242 Ile 241 Leu 240 Phe 239 Leu 238 Thr 237 Tyr 236 Phe 235 Leu 234 Pro 233 Leu 232 Arg 231 Arg 230

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M1-M2 Linker

Ser 259 Asp 260 Glu 261 Gly 262 Glu 263 Lys 264 Leu 265 Ser 266

 

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M2

Pro 287 Ile 286 Leu 267 Ser 268 Thr 269 Ser 270 Val 271 Leu 272 Val 273 Ser 274 Leu 275 Thr 276 Val 277 Phe 278 Leu 279 Leu 280 Val 281 Ile 282 Glu 283 Glu 284 Ile 285

Residues with mutations: [Val 273]

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M2-M3 Linker

Ser 288 Ser 289 Ser 290 Lys 291 Val 292 Ile 293 Pro 294 Leu 295

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M3

 

Asn 319 Ile 318 Val 317 Phe 316 Val 315 Ile 296 Gly 297 Glu 298 Tyr 299 Leu 300 Leu 301 Phe 302 Ile 303 Met 304 Ile 305 Phe 306 Val 307 Thr 308 Leu 309 Ser 310 Ile 311 Ile 312 Val 313 Thr 314

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M3-M4 Linker

Gln 417 Val 416 Val 415 Gln 414 Ser 413 Ile 412 Phe 411 His 410 Glu 409 Lys 408 Lys 407 Val 406 His 405 Arg 404 Ser 403 Ile 402 Tyr 401 Arg 400 Ile 399 Ser 398 Asp 397 Ala 396 Ala 395 Lys 394 Glu 393 Leu 392 Phe 391 Ala 390 Val 389 Leu 388 Val 387 Lys 386 Glu 385 Gly 384 Asp 383 Ser 382 Leu 381 Gln 380 Lys 379 Gln 378 Lys 377 Lys 376 Lys 375 Glu 374 Leu 373 Val 372 Lys 371 Gly 370 Lys 369 Val 368 Val 367 Pro 366 Gln 365 Ser 364 Glu 363 Glu 362 Lys 361 Glu 360 Pro 359 Ser 358 Ser 357 Tyr 356 Arg 355 Asp 354 Val 353 His 352 Asp 351 Lys 350 Met 349 Cys 348 Leu 347 Leu 346 Lys 345 Pro 344 Leu 343 Lys 342 Gln 341 Leu 340 Phe 339 Leu 338 Arg 337 Lys 336 Val 335 Trp 334 Pro 333 Ala 332 Met 331 Pro 330 His 329 Tyr 328 Thr 327 Ser 326 Ser 325 Ser 324 Arg 323 His 322 His 321 Val 320

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M4

 

Asp 418 Trp 419 Lys 420 Phe 421 Val 422 Ala 423 Gln 424 Val 425 Leu 426 Asp 427 Arg 428 Ile 429 Phe 430 Leu 431 Trp 432 Leu 433 Phe 434 Leu 435 Ile 436 Val 437 Ser 438 Val 439 Thr 440 Gly 441 Ser 442 Val 443 Leu 444 Ile 445 Phe 446 Thr 447 Pro 448 Ala 449 Leu 450 Lys 451 Met 452 Trp 453 Leu 454 His 455 Ser 456 Tyr 457 His 458

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Alignment