Zinc-Activated Channel (ZAC)


ZAC Receptor Description

Click on sections of the picture to learn more about research on individual amino acids. Numbering of the ZAC subunit sequences start at the beginning of the mature protein. Only amino acids in the mature protein are shown.

 

amino acid all

ZAC -- GENBANK

ZAC -- FASTA

ZAC -- Alignment

ZAC -- Publications


 

 

 

 


 

 

 


N-Terminus

Gln 1 Gly 2 Phe 3 Gln 4 Gly 5 Thr 6 Ala 7 Ala 8 Ile 9 Trp 10 Pro 11 Ser 12 Leu 13 Phe 14 Asn 15 Val 16 Asn 17 Leu 18 Ser 19 Lys 20 Lys 21 Val 22 Gln 23 Glu 24 Ser 25 Ile 26 Gln 27 Ile 28 Pro 29 Asn 30 Asn 31 Gly 32 Ser 33 Ala 34 Pro 35 Leu 36 Lea37 Val 38 Asp 39 Val40 Arg 41 Val 42 Phe 43 Val 44 Ser 45 Asn 46 Val 47 Phe 48 Asn 49 Val 50 Asp 51 Ile 52 Leu 53 Arg 54 Tyr  55 thr 56 Met 57 Ser 58 Ser 59 Met 60 Leu 61 Leu 62 Leu 63 Arg 64 Leu 65 Ser 66 Trp 67 Leu 68 Asp 69 Thr 70 Arg 71 Leu 72 Ala 73 Trp 74 Asn 75 Thr 76 Ser 77 Ala 78 His 79 Pro 80 Arg 81 His 82 Ala 83 Ile 84 Thr 85 Leu 86 Pro 87 Trp 88 Glu 89 Ser 90 Leu 91 Trp 92 Thr 93 Pro 94 Arg 95 Leu 96 Thr 97 Ile98 Leu 99 Glu 100 Ala 101 Leu 102 Trp 103 Val 104 Asp 105 Trp 106 Arg 107 Asp 108 Gln 109 Ser 110 Pro 111 Gln 112 Ala 113 Arg 114 Val 115 Asp 116 Gln 117 Asp 118 Gly119 His 120 Val 121 Lys 122 Leu 123 Asn 124 Leu 125 Ala 126 Leu 127 Thr 128 Thr 129 Glu 130 Thr 131 Asn 132 Cys 133 Asn 134 Phe 135 Glu136 Leu 137 Leu 138 His 139 Phe 140 Phe 141 Arg 142 Asp 143 His 144 Ser 145 Asn 146 Cys 147 Ser 148 Leu 149 Ser 150 Phe 151 Tyr 152 Ala 153 Leu 154 Ser 155 Asn 156 Thr 157 Ala 158 Met 159 Leu 160 Glu 161 Phe 162 Gln 163 Ala 164 his 165 Val 166 Val 167 Asn 168 Glu 169 Ile 170 Val 171 Ser 172 Val 173 Lys 174 Arg 175 Glu 176 Tyr 177 Val 178 Val 179 Tyr 180 Asp 181 Leu 182 Lys 183 Thr 184 Gln 185 Val 186 Pro 187 Pro 188 GLn 189 Gln 190 Leu 191 Val 192 Pro 193 Cys 194 Phe 195 Gln 196 Val 197 Thr 198 Leu 199 Arg 200 Leu 201 Lys 202 Asn 203 Thr 204 Ala 205

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M1

Leu 206 Lys 207 Ser 208 Ile 209 Ile 210 Ala 211 Leu 212 Leu 213 Val 214 Pro 215 Ala 216 Glu 217 Ala 218 Leu 219 Leu 220 Leu 221 Ala 222 Asp 223 Val 224 Cys 225 Gly 226 Gly 227 Leu 228

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M1-M2 Linker

Leu 229 Pro 230 Leu 231 Arg 232 Ala 233 Ile 234 Glu 235 Arg 236


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M2

Ile 237 Gly 238 Tyr 239 Lys 240 Val 241 Tyr 242 Leu 243 Leu 244 Leu 245 Ser 246 Tyr 247 Leu 248 Val 249 Leu 250 His 251 Ser 252 Ser 253 Leu 254 Val 254

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M2-M3 Linker

Gln 255 Ala 256 Leu 257 Pro 258 Ser 259 Ser 269 Ser 261 Ser 262 Cys 263 Asn 264

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M3

Pro 265 Leu 266 Leu 267 Ile 268 Tyr 269 Tyr 270 Phe 271 Thr 272 Ile 273  Leu 274 Leu 275 Leu 276 Leu 277 Leu 278 Phe 279 Leu 280 Ser 281 Thr 282 Ile 283 Glu 284

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M3-M4 Linker

Thr 285 Val 286 Leu 287 Leu 288 Ala 289 Gly 290 Leu 291 Leu 292 Ala 293 Arg 294 Gly 295 Asn 296 Leu 297 Gly 298 Ala 299 Lys 300 Ser 301 Gly 302 Pro 303 Ser 304 Pro 305 Ala 306 Pro 307 Arg 308 Gly 309 Glu 310 Gln 311 Arg 312 Glu 313 His 314 Gly 315 Asn 316 Pro 317 Gly 318 Pro 319 His 320 Pro 321 Ala 322 Glu 323 Glu 324 Pro 325 Ser 326 Arg 327 Gly 328 Val 329 Lys 330 Gly 331 Ser 332 Gln 333 Arg 334 Ser 335 Trp 336 Pro 337 Glu 338 Thr 339 Ala 340 Asp 341 Arg 342 Ile 343 Phe 344 Phe 345 Leu 346 Val 347
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M4

Tyr 348 Val 349 Val 350 Gly 351 Val 352 Leu 353 Cys 354 Thr 355 Gln 356 Phe 357 Val 358 Phe 359 Ala 360 Gly 361 Ile 362 Trp 363 Met 364 Trp 365 Ala 366 Ala 367 Cys 368 Lys 369 Ser 370 Asp 371 Ala 372 Ala 373 Pro 374 Gly 375 Glu 376 Ala 377 Ala 378 Pro 379 His 380 Gly 381 Arg 382 Arg 383 Pro 384 Arg 385 Leu 386

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**No comparative alignment available for human, mouse, and rat.

ZAC is present in the human, chimpanzee, dog, cow, and opossum genome, but is functionally absent from mouse, or rat, genomes. (Davies et al., 2003; Houtani et al., 2005)