GABAA subunit q

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

GABAA q - GENBANK

GABAA q - FASTA

GABAA q - Alignment

 

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Lys 237 Leu 236 Ile 235 Leu 234 Arg 233 Ile 232 Tyr 231 Ser 230 Gly 229 Thr 228 Tyr 247 Ser 246 Asn 245 Val 244 Glu 243 Arg 242 Gln 241 Val 240 Gln 239 Phe 238 Tyr 227 Ser 17 His 12 Phe 11 Glu 1 Gly 2 Asn 3 Tyr 4 Pro 7 Ile 8 Ser 16 Pro 5 Val 23 Phe 15 Ala 18 Val 22 Glu 21 Pro 20 Val 19 Glu 14 Phe 13 Lys 10 Pro 9 Ser 6 Arg 48 Glu 35 Asn 34 Ala 33 Leu 24 Asn 25 Leu 26 Phe 27 Ser 47 Asn 28 Cys 29 Lys 30 Asn 31 Cys 32 Val 38 Gln 39 Ala 36 Val 37 Lys 40 Ile 41 Leu 42 Asp 43 Arg 44 Val 45 Leu 46 Tyr 49 Asp 50 Val 51 Arg 52 Leu 53 Arg 54 Pro 55 Asn 56 Phe 57 Gly 58 Gly 59 Ala 60 Pro 61 Val 62 Pro 63 Val 64 Arg 65 Ile 66 Ser 67 Ile 68 Tyr 69 Val 70 Thr 71 Ser 72 Ile 73 Glu 74 Gln 75 Ile 76 Ser 77 Glu 78 Met 79 Asn 80 Met 81 Asp 82 Tyr 83 Thr 84 Ile 85 Thr 86 Met 87 Phe 88 Phe 89 His 90 Gln 91 Thr 92 Trp 93 Lys 94 Asp 95 Ser 96 Arg 97 Leu 98 Ala 99 Tyr 100 Tyr 101 Glu 102 Thr 103 Thr 104 Leu 105 Asn 106 Leu 107 Thr 108 Leu 109 Asp 110 Tyr 111 Arg 112 Met 113 His 114 Glu 115 Lys 116 Leu 117 Trp 118 Val 119 Pro 120 Asp 121 Cys 122 Tyr 123 Phe 124 Leu 125 Asn 126 Ser 127 Lys 128 Asp 129 Ala 130 Phe 131 Val 132 His 133 Asp 134 Val 135 Thr 136 Val 137 Glu 138 Asn 139 Arg 140 Val 141 Phe 142 Gln 143 Leu 144 His 145 Pro 146 Asp 147 Gly 148 Thr 149 Val 150 Arg 151 Tyr 152 Gly 153 Ile 154 Arg 155 Leu 156 Thr 157 Thr 158 Thr 159 Ala 160 Ala 161 Cys 162 Ser 163 Leu 164 Asp 165 Leu 166 His 167 Lys 168 Phe 169 Pro 170 Met 171 Asp 172 Lys 173 Gln 174 Ala 175 Cys 176 Asn 177 Leu 178 Val 179 Val 180 Glu 181 Ser 182 Tyr 183 Gly 184 Tyr 185 Thr 186 Val 187 Glu 188 Asp 189 Ile 190 Ile 191 Leu 192 Phe 193 Trp 194 Thr 204 Met 203 His 202 Ile 201 Ala 200 Asn 199 Gly 198 Asn 197 Asp 196 Asp 195 Glu 205 Glu 206 Leu 207 His 208 Ile 209 Pro 210 Gln 211 Phe 212 Thr 213 Phe 214 Leu 215 Gly 216 Arg 217 Thr 218 Ile 219 Thr 220 Ser 221 Lys 222 Glu 223 Val 224 Tyr 225 Phe 226

 

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M1

Trp 267 Leu 248 Val 249 Gln 250 Val 251 Tyr 252 Trp 253 Pro 254 Thr 255 Val 256 Leu 257 Thr 258 Thr 259 Ile 260 Thr 261 Ser 262 Trp 263 Ile 264 Ser 265 Phe 266

 

 

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M1-M2 Linker

 

 

Met 268 Asn 269 Tyr 270 Asp 271

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M2

Ser 272 Ser 273 Ala 274 Ala 275 Arg 276 Val 277 Thr 278 Ile 279 Gly 280 Leu 281 Thr 282 Ser 283 Met 284 Leu 285 Ile 286 Leu 287 Thr 288 Thr 289 Ile 290 Asp 291 Ser 292

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M2-M3 Linker

 

His 293 Leu 294 Arg 295 Asp 296 Lys 297 Leu 298 Pro 299 Asn 300 Ile 301 Ser 302 Cys 303 Ile 304

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M3

 

Lys 305 Ala 306 Ile 307 Asp 308 Ile 309 Tyr 310 Ile 311 Leu 312 Val 313 Cys 314 Leu 315 Phe 316 Phe 317 Val 318 Phe 319 Leu 320 Ser 321 Leu 322 Leu 323 Glu 324

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M3-M4 Linker

Tyr 582 Pro 580 Asp 576 Leu 577 Asn 579 Asp 581 Val 583 Pro 584 Lys 585 Val 586 Asp 587 Gly 572 Phe 575 Phe 578 Glu 556 Ser 555 Ser 554 Ser 553 Asp 552 Glu 550 Gly 548 His 547 Ala 546 Met 545 Leu 544 Glu 543 Asp 542 Asp 541 Asn 540 Gln 549 Cys 522 Leu 523 Ala 524 Ile 525 Lys 526 Glu 527 Gln 528 Phe 529 Lys 530 Cys 531 Asp 532 Thr 533 Asn 534 Ser 535 Thr 536 Trp 537 Gly 538 Leu 539 Asp 518 Lys 519 Ser 520 Asp 521 Asn 517 Asn 516 Asp 515 Asp 514 Leu 513 Asp 512 Trp 511 Gly 510 Ala 509 Glu 508 Gln 507 Val 506 Gly 505 Lys 504 Glu 503 Gly 502 His 501 His 500 Leu 499 Met 498 Pro 497 Lys 496 Gly 495 Ser 494 Pro 493 Gly 492 His 491 Gly 490 His 489 Arg 488 Glu 487 Asp 486 Lys 551 Ser 485 Ser 484 Leu 483 Ser 482 Glu 481 Asn 480 Ser 479 Asp 478 Glu 477 His 476 Asp 475 His 474 Thr 473 Val 472 Gly 471 His 470 Gly 469 His 468 Ala 467 Glu 466 Val 465 Asn 463 Arg 464 His 441 Arg 440 Ala 439 Leu 432 Pro 433 Ser 434 Thr 435 Ser 436 Glu 437 Gln 438 Ser 442 Tyr 443 Gly 444 Val 445 Arg 446 Phe 447 Asn 448 Gly 449 Phe 450 Gln 451 Ala 452 Asp 453 Asp 454 Ser 455 Ile 457 Pro 458 Thr 459 Glu 460 Asp 431 Ser 430 Leu 429 Ser 428 Glu 427 Gly 426 Thr 425 Ala 424 Leu 423 Pro 422 Ala 421 Gln 420 Gly 419 Ser 418 Leu 417 Ser 416 Thr 415 Leu 414 Pro 413 Ser 412 Leu 411 Ser 410 Glu 409 Ser 408 Thr 407 Ala 406 Leu 405 Gln 404 Ala 403 Lys 588 Ser 574 Phe 573 Tyr 325 Val 326 Tyr 327 Ile 328 Asn 329 Tyr 330 Leu 331 Phe 332 Tyr 333 Ser 334 Arg 335 Gly 336 Pro 337 Arg 338 Arg 339 Gln 340 Pro 341 Arg 342 Arg 343 His 344 Arg 345 Arg 346 Pro 347 Arg 348 Arg 349 Val 350 Ile 351 Ala 352 Arg 353 Tyr 354 Arg 355 Tyr 356 Gln 358 Gln 357 Val 359 Val 360 Val 361 Gly 362 Asn 363 Val 364 Gln 365 Asp 366 Gly 367 Leu 368 Thr 397 Leu 396 Ser 395 Gly 394 Leu 393 Ser 392 Glu 391 Pro 390 Ser 389 Ala 388 Leu 387 Pro 386 Ala 385 Gln 384 Ala 383 Pro 382 Thr 381 Ile 380 Pro 379 Leu 378 Ser 377 Ser 376 Val 375 Gly 374 Asp 373 Glu 372 Val 371 Asn 370 Ile 369 Ser 398 Thr 399 Ser 400 Glu 401 Gln 402 Ile 456 Ile 461 Arg 462 Ser 557 Glu 558 Asp 559 Ser 560 Cys 561 Pro 562 Pro 563 Ser 564 Pro 565 Gly 566 Cys 567 Ser 568 Phe 569 Thr 570 Glu 571

 

back to top Ile 367 Asn 368 Val 369 Glu 370 Asp 371 Gly 372 Val 373 Ser 374 Ser 375 Leu 376 Ile 378 Thr 379 Pro 380 Ala 381 Gln 382 Ala 383 Pro 384 Leu 385 Ala 386 Ser 387 Pro 388 Glu 389 Ser 390 Leu 391 Gly 392 Ser 393 Leu 394 Thr 395

M4

Trp 589 Ser 590 Arg 591 Phe 592 Leu 593 Phe 594 Pro 595 Leu 596 Ala 597 Phe 598 Gly 599 Leu 600 Phe 601 Asn 602 Ile 603 Val 604 Tyr 605 Trp 606 Val 607 Tyr 608 His 609 Met 610 Tyr 611

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Alignment