GABAA subunit r1

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

GABAA r1 - GENBANK

GABAA r1 - FASTA

GABAA r1 - Alignment

 

 

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Thr 236 Thr 235 Thr 255 Leu 256 Arg 257 Arg 258 His 259 Lys 237 Leu 238 Ala 239 Phe 240 Tyr 241 Ser 242 Ser 243 Thr 244 Gly 245 Ile 252 Tyr 251 Leu 250 Arg 249 Asn 248 Trp 246 Tyr 247 Phe 254 Asn 253 Thr 1 Glu 2 Ser 3 Arg 4 Met 5 Arg 25 Gln 24 His 6 Trp 7 Pro 8 Gly 9 Arg 10 Glu 11 Val 12 His 13 Glu 14 Met 15 Ser 16 Lys 17 Lys 18 Gly 19 Arg 20 Pro 21 Gln 22 Arg 23 His 33 Arg 26 Glu 27 Val 28 His 29 Glu 30 Asp 31 Ala 32 Lys 34 Leu 58 Arg 59 Gln 35 Leu 57 Gln 56 Glu 55 Ser 54 Lys 53 Thr 52 Leu 51 Pro 50 Ser 49 Lys 48 Thr 47 Ile 46 Asp 45 Pro 44 Ser 43 Arg 42 Arg 41 Leu 40 Ile 39 Pro 38 Val 36 Ser 37 Ile 60 Asp 61 Asp 62 His 63 Asp 64 Phe 65 Ser 66 Met 67 Arg 68 Pro 69 Gly 70 Ala 75 Pro 74 Gly 73 Gly 72 Phe 71 Ile 76 Pro 77 Val 78 Gly 79 Val 80 Asp 81 Val 82 Gln 83 Val 84 Glu 85 Ser 86 Leu 87 Asp 88 Ser 89 Ile 90 Ser 91 Glu 92 Val 93 Asp 94 Met 95 Asp 96 Phe 97 Thr 98 Met 99 Thr 100 Leu 101 Tyr 102 Leu 103 Arg 104 His 105 Tyr 106 Trp 107 Lys 108 Asp 109 Glu 110 Asp 125 Phe 124 Thr 123 Met 122 Ser 121 Leu 120 Asn 119 Asn 118 Thr 117 Ser 116 Pro 115 Phe 114 Ser 113 Leu 112 Arg 111 Gly 126 Ile 132 Lys 131 Lys 130 Val 129 Leu 128 Arg 127 Trp 133 Val 134 Pro 135 Asp 136 Met 137 Phe 138 Phe 139 Val 140 His 141 Ser 142 Lys 143 Arg 144 Ser 145 Phe 146 Ile 147 His 148 Asp 149 Thr 150 Thr 151 Thr 152 Asp 153 Asn 154 Val 155 Met 156 Leu 157 Arg 158 Val 159 Val 173 Thr 172 Val 171 Arg 170 Leu 169 Ser 168 Tyr 167 Leu 166 Val 165 Lys 164 Gly 163 Asp 162 Pro 161 Gln 160 Asp 180 Met 179 Asn 178 Cys 177 Met 176 Ala 175 Thr 174 Phe 181 Ser 182 Arg 183 Phe 184 Pro 185 Leu 186 Asp 187 Thr 188 Gln 189 Thr 190 Cys 191 Ser 192 Leu 193 Gly 212 Asn 213 Lys 211 Lys 210 Trp 209 Tyr 208 Leu 207 Met 206 Leu 205 Asp 204 Asp 203 Glu 202 Thr 201 Tyr 200 Ala 199 Tyr 198 Ser 197 Glu 196 Glu 220 Asp 219 Thr 218 Lys 217 Leu 216 Ser 215 Asp 214 Glu 194 Ile 195 Arg 221 Ile 222 Ser 223 Leu 224 Ser 225 Gln 226 Phe 227 Leu 228 Ile 229 Gln 230 Glu 231 Phe 232 His 233 Thr 234

 

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M1

Ile 260 Phe 261 Phe 262 Phe 263 Leu 264 Leu 265 Gln 266 Thr 267 Tyr 268 Pro 270 Phe 269 Val 275 Thr 272 Leu 273 Met 274 Ala 271 Met 276

 

 

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M1-M2 Linker

 

 

Phe 282 Ser 281 Arg 286 Trp 283Asp 285 Ile 284 Ala 261 Arg 287 Leu 277 Ser 278 Trp 279 Val 280 Ala 261

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M2

Gly 309 Val 310 Ala 288 Val 289 Pro 290 Ala 291 Arg 292 Val 293 Pro 294 Leu 295 Gly 296 Ile 297 Thr 298 Thr 299 Val 300 Leu 301 Thr 302 Met 303 Ser 304 Thr 305 Ile 306 Ile 307 Thr 308

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M2-M3 Linker

 

Asn 311 Ala 312 Ser 313 Met 314 Pro 315 Arg 316 Val 317 Ser 318 Tyr 319 Ile 320 Lys 321 Ala 322

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M3

 

Val 323 Asp 324 Ile 325 Tyr 326 Leu 327 Trp 328 Val 329 Ser 330 Phe 331 Val 332 Phe 333 Val 334 Phe 335 Leu 336 Ser 337 Val 338 Leu 339

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M3-M4 Linker

Arg 439 Ser 438 Tyr 437 Lys 436 Glu 340 Tyr 341 Ala 342 Ala 343 Val 344 Asn 345 Tyr 346 Leu 347 Thr 348 Thr 349 Val 350 Gln 351 Glu 352 Arg 353 Lys 354 Glu 355 Gln 356 Lys 357 Leu 358 Arg 359 Glu 360 Lys 361 Leu 362 Pro 363 Cys 364 Thr 365 Ser 366 Gly 367 Leu 368 Pro 369 Pro 370 Pro 371 Arg 372 Thr 373 Ala 374 Met 375 Leu 376 Asp 377 Gly 378 Asn 379 Tyr 380 Ser 381 Asp 382 Gly 383 Glu 384 Val 385 Asn 386 Asp 387 Leu 388 Asp 389 Asn 390 Tyr 391 Met 392 Pro 393 Glu 394 Asn 395 Gly 396 Glu 397 Lys 398 Pro 399 Gln 400 Arg 401 Met 402 Met 403 Val 404 Gln 405 Leu 406 Thr 407 Leu 408 Ala 409 Ser 410 Glu 411 Arg 412 Ser 413 Ser 414 Pro 415 Gln 416 Arg 417 Lys 418 Ser 419 Gln 420 Arg 421 Ser 422 Ser 423 Tyr 424 Val 425 Ser 426 Met 427 Arg 428 Ile 429 Asp 430 Thr 431 His 432 Ala 433 Ile 434 Asp 435

 

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M4

Ile 440 Ile 441 Phe 442 Pro 443 Ala 444 Ala 445 Tyr 446 Ile 447 Leu 448 Phe 449 Asn 450 Leu 451 Ile 452 Tyr 453 Trp 454 Ser 455 Ile 456 Phe 457 Ser 458

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Alignment