GABAA subunit g2

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

GABAA g2 - GENBANK

GABAA g2 - FASTA

GABAA g2 - Alignment

 

 

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Gln 1 Lys 2 Ser 3 Asp 4 Asp 5 Asp 6 Tyr 7 Glu 8 Asp 9 Tyr 10 Ala 11 Ser 12 Asn 13 Lys 14 Thr 15 Trp 16 Val 17 Leu 18 Thr 19 Pro 20 Lys 21 Val 22 Pro 23 Glu 24 Gly 25 Asp 26 Val 27 Thr 28 Val 29 Ile 30 Leu 31 Asn 32 Asn 33 Leu 34 Leu 35 Glu 36 Gly 37 Lys 38 Asp 39 Asn 40 Lys 41 Leu 42 Arg 43 Pro 44 Asp 45 Ile 46 Gly 47 Val 48 Lys 49 Pro 50 Thr 51 Leu 52 Ile 53 His 54 Thr 55 Asp 56 Met 57 Tyr 58 Val 59 Asn 60 Ser 61 Ile 62 Gly 63 Pro 64 Val 65 Asn 66 Ala 67 Ile 68 Asn 69 Met 70 Glu 71 Tyr 72 Thr 73 Ile 74 Asp 75 Ile 76 Phe 77 Phe 78 Ala 79 Gln 80 Thr 81 Trp 82 Tyr 83 Asp 84 Arg 85 Arg 86 Leu 87 Lys 88 Phe 89 Asn 90 Ser 91 Thr 92 Ile 93 Lys 94 Val 95 Leu 96 Arg 97 Leu 98 Asn 99 Ser 100 Asn 101 Met 102 Val 103 Gly 104 Lys 105 Ile 106 Trp 107 Ile 108 Pro 109 Asp 110 Thr 111 Phe 112 Phe 113 Arg 114 Asn 115 Ser 116 Lys 117 Lys 118 Ala 119 Asp 120 Ala 121 His 122 Trp 123 Ile 124 Thr 125 Thr 126 Pro 127 Asn 128 Arg 129 Met 130 Leu 131 Arg 132 Ile 133 Trp 134 Asn 135 Asp 136 Gly 137 Arg 138 Val 139 Leu 140 Tyr 141 Thr 142 Leu 143 Arg 144 Leu 145 Thr 146 Ile 147 Asp 148 Ala 149 Glu 150 Cys 151 Gln 152 Leu 153 Gln 154 Leu 155 His 156 Asn 157 Phe 158 Pro 159 Met 160 Asp 161 Glu 162 His 163 Ser 164 Cys 165 Pro 166 Leu 167 Glu 168 Phe 169 Ser 170 Ser 171 Tyr 172 Gly 173 Tyr 174 Pro 175 Arg 176 Glu 177 Glu 178 Ile 179 Val 180 Tyr 181 Gln 182 Trp 183 Lys 184 Arg 185 Ser 186 Ser 187 Val 188 Glu 189 Val 190 Gly 191 Asp 192 Thr 193 Arg 194 Ser 195 Trp 196 Arg 197 Leu 198 Tyr 199 Gln 200 Phe 201 Ser 202 Phe 203 Val 204 Gly 205 Leu 206 Arg 207 Asn 208 Thr 209 Thr 210 Glu 211 Val 212 Val 213 Lys 214 Thr 215 Thr 216 Ser 217 Gly 218 Asp 219 Tyr 220 Val 221 Val 222 Met 223 Ser 224 Val 225 Tyr 226 Phe 227 Asp 228 Leu 229 Ser 230 Arg 231 Arg 232 Met 233 Gly 234

Residues with Mutations: [ Arg 43 ]

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M1

Tyr 235 Phe 236 Thr 237 Ile 238 Gln 239 Thr 240 Tyr 241 Ile 242 Pro 243 Cys 244 Thr 245 Leu 246 Ile 247 Val 248 Val 249 Leu 250 Ser 251 Trp 252 Val 253 Ser 254 Phe 255 Trp 256

 

 

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M1-M2 Linker

 

 

Ile 257 Asn 258 Lys 259 Asp 260 Ala 261

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M2

Val 262 Pro 263 Ala 264 Arg 265 Thr 266 Ser 267 Leu 268 Gly 269 Ile 270 Thr 271 Thr 272 Val 273 Leu 274 Thr 275 Met 276 Thr 277 Thr 278 Leu 279 Ser 280 Thr 281 Ile 282

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M2-M3 Linker

Residues with Mutations: [ Lys 289 ]

Ala 283 Arg 284 Lys 285 Ser 286 Leu 287 Pro 288 Lys 289 Val 290 Ser 291 Tyr 292 Val 293 Thr 294

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M3

 

Ala 294 Met 295 Asp 296 Leu 297 Phe 298 Val 299 Ser 300 Val 301 Cys 302 Phe 303 Ile 304 Phe 305 Val 306 Phe 307 Ser 308 Ala 309 Leu 310 Val 311 Glu 312 Tyr 313 Gly 314 Thr 315

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M3-M4 Linker

Leu 316 His 317 Tyr 318 Phe 319 Val 320 Ser 321 Asn 322 Arg 323 Lys 324 pro 325 Ser 326 Lys 327 Asp 328 Lys 329 Asp 330 Lys 331 Lys 332 Lys 333 Lys 334 Asn 335 Pro 336 Leu 337 Leu 338 Arg 339 Met 340 Phe 341 Ser 342 Phe 343 Lys 344 Ala 345 Pro 346 Thr 347 Ile 348 Asp 349 Ile 350 Arg351 Pro 352 Arg 353 Ser 354 Ala 355 Thr 356 Ile 357 Gln 358 Met 359 Asn 360 Asn 361 Ala 362 Thr 363 His 364 Lys 365 Gln 366 Glu 367 Arg 368 Asp 369 Glu 370 Glu 371 Tyr 372 Gly 373 Tyr 374 Glu 375 Cys 376 Leu 377 Asp 378 Gly 379 Lys 380 Asp 381 Cys 382 Ala 383 Ser 384 Phe 385 Phe 386 Cys 387 Cys 388 Phe 389 Glu 390 Asp 391 Cys 392 Arg 393 Thr 394 Gly 395 Ala 396 Trp 397 Arg 398 His 399 Gly 400 Arg 401 Ile 402 His 403 Ile 404 Arg 405 Ile 406 Ala 407 Lys 408 Met 409 Asp 410 Ser 411

 

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M4

Tyr 412 Ala 413 Arg 414 Ile 415 Phe 416 Phe 417 Pro 418 Thr 419 Ala 420 Phe 421 Cys 422 Leu 423 Phe 424 Asn 425 Leu 426 Val 427 Tyr 428 Trp 429 Val 430 Ser 431 Tyr 432 Leu 433 Tyr 434 Leu 435

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Alignment