GABAA subunit a4

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

GABAA a4 -- GENBANK

GABAA a4 -- FASTA

GABAA a4 -- Alignment

 

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Lys 224Arg 224 Gly 224Tyr 224Met 224 Thr 20 Asn 2 Leu 1 Glu 11 Gln 28 Gln 28 Gln 28 Thr 43 Glu 44 Val 45 Val 42 Pro 41 Gly 40 Gly 39 Phe 38 Gly 37 Pro 36 Arg 35 Leu 34 Arg 33 Asn 32 Asp 31 Tyr 30 Glu 12 Phe 19 Asp 37 Gln 28 Leu 14 Lys 13 Cys 15 Asn 18 Glu 17 Thr 16 Arg 21 Ile 22 Leu 23 Asp 24 Ser 25 Leu 26 Gly 29 Asp 28 Leu 27 Lys 46 Thr 47 Asp 48 Ile 49 Tyr 50 Val 51 Thr 52 Ser 53 Phe 54 Gly 55 Pro 56 Val 57 Ser 58 Tyr 64 Glu 63 Met 62 Glu 61 Val 60 Asp 59 Gln 72 Thr 65 Met 66 Asp 67 Val 68 Phe 69 Phe 70 Arg 71 Thr 73 Trp 74 Ile 75 Asp 76 Lys 77 Ile 85 Pro 84 Gly 83 Asp 82 Tyr 81 Lys 80 Leu 79 Arg 78 Arg 106 Phe 105 Phe 104 Thr 103 Asp 102 Pro 101 Thr 100 Trp 99 Val 98 Lys 97 Thr 96 Val 95 Met 94 Met 93 Asn 92 Asn 91 Ile 87 Glu 86 Leu 88 Arg 89 Leu 90 Ala 118 Gly 108 Lys 109 Lys 110 Ser 111 Val 112 Ser 113 Asn 115 Met 116 Thr 117 His 114 Leu 132 Ile 131 Asn 120 Lys 121 Leu 122 Phe 123 Arg 124 Ile 125 Met 126 Arg 127 Asn 128 Gly 129 Thr 130 Tyr 133 Thr 134 Met 135 Arg 136 Leu 137 Thr 138 Ile 139 Ser 140 Ala 141 Glu 142 Cys 143 Pro 119 Asn 107 His 155 Gly 154 Asp 153 Met 152 Pro 151 Phe 150 Asp 149 Val 148 Leu 147 Arg 146 Met 145 Pro 144 Tyr 164 Ser 163 Pro 158 Leu 159 Lys 160 Phe 161 Gly 162 Lys 177 Thr 176 Trp 175 Thr 174 Tyr 173 Ile 172 Met 171 Glu 170 Ser 169 Lys 168 Pro 167 Tyr 166 Ala 165 Gly 178 Pro 179 Glu 180 Lys 181 Ser 182 Val 183 Glu 184 Val 185 Pro 186 Lys 187 Glu 188 Ser 189 Ser 190 Ser 191 Leu 192 Val 193 Gln 194 Tyr 195 Asp 196 Leu 197 Ile 198 Thr 206 Glu 205 Gly 199 Gln 200 Thr 201 Val 202 Ser 203 Ser 204 Ile 207 Ala 156 Val 219 Thr 218 Met 217 Val 216 Ile 215 Glu 213 Gly 212 Thr 211 Ile 210 Ser 209 Lys 208 Tyr 214 Gln 9 Gln 7 Cys 157 Lys 10 Asn 8 Tyr 220 Phe 221 His 222 Leu 223 Arg 224 Gly 6 Pro 5 Ser 4 Glu 3

 

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M1

Ile 245 Phe 225 Met 226 Ile 227 Gln 228 Thr 229 Tyr 230 Ile 231 Pro 232 Cys 233 Ile 234 Met 235 Thr 236 Val 237 Ile 238 Leu 239 Ser 240 Gln 241 Val 242 Ser 243 Phe 244 Trp 245

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M1-M2 Linker

Asn 246 Lys 247 Glu 248 Ser 249 back to top

 

M2

Ser 270 Val 250 Pro 251 Ala 252 Arg 253 Thr 254 Val 255 Phe 256 Gly 257 Ile 258 Thr 259 Thr 260 Val 261 Leu 262 Thr 263 Met 264 Thr 265 Thr 266 Leu 267 Ser 268 Ile 269 Ala 271 back to top

 

M2-M3 Linker

Thr 282 Ala 281 Tyr 280 Ser 279 Val 278 Arg 272 His 273 Ser 274 Leu 275 Pro 276 Lys 277 back to top

 

M3

 

Ala 283 Met 284 Asp 285 Trp 286 Phe 287 Ile 288 Ala 289 Val 290 Cys 291 Phe 292 Ala 293 Phe 294 Val 295 Phe 296 Ser 297 Ala 298 Leu 299 Ile 300 Glu 301 Phe 302 Ala 303 Ala 304 back to top

 

M3-M4 Linker

Ser 371 Pro 372 Pro 373 Pro 374 Thr 387 Lys 379 Gly 378 Val 371 Asn 372 Thr 373 Thr 374 Gly 375 Ala 376 Ser 375 Gln 314 Arg 313 Thr 322 His 321 Gly 318 Val 320 Arg 316 Thr 309 Lys 311 Ser 317 Phe 319 Ser 323 Ile 312 Leu 315 Thr 310 Arg 321 Arg 321 Ala 309 Lys 315 Pro 325 Ala 314 Ser 323 Tyr 319 Pro 317 Ser 310 Ser 313 Arg 316 Gly 320 Thr 324 Met 318 Thr 321 Ile 322 Val 312 Gly 311 Ala 347 Ser 334 Thr 345 Ala 339 Leu 338 Ser 336 Ala 335 Pro 337 Ile 344 Ser 343 Ala 342 Ala 341 Arg 340 Ala 347 Glu 346 Arg 334 Ala 340 Asn 346 Pro 338 Lys 336 Glu 335 His 337 Pro 341 Leu 342 Gln 343 Asn 344 Thr 345 Ala 347 Asn 346 Ser 354 Arg 353 Ala 352 Phe 355 Pro 356 Asn 357 Pro 358 Ser 359 Ser 360 Ala 361 Asn 351 Arg 365 Ser 364 Tyr 363 Leu 362 Val 375 Val 374 Gln 373 Glu 372 Ser 371 Ser 370 Lys 369 Gly 368 Thr 367 Pro 366 Phe 308 Ser 397 Gly 396 Ala 391 Ser 400 Ser 395 Gly 398 Pro 393 Val 306 Asn 307 Tyr 308 Thr 309 Lys 319 Gln 325 Lys 317 Pro 323 Thr 320 Ile 311 Arg 318 Ser 321 Ala 316 Glu 326 Glu 314 Pro 324 Asn 310 Lys 315 Lys 322 Gln 312 Met 313 Pro 328 Val 327 Ala 329 Ala 330 Pro 331 Gln 333 Val 332 Arg 334 Ala 340 Glu 339 Pro 338 Lys 336 Glu 335 His 337 Pro 341 Leu 342 Gln 343 Asn 344 Thr 345 Met 351 Asn 350 Leu 349 Asn 348 Ala 347 Asn 346 Val 365 Asp 364 Ser 363 Glu 362 Ser 361 His 360 Val 359 Leu 358 Ala 357 Asm 356 Thr 355 Arg 352 Lys 353 Arg 354 Ser 376 Ser 375 His 374 Asn 373 Gly 372 Val 371 Glu 370 Thr 369 Arg 368 Asn 367 Gly 366 Lys 377 Ser 378 Ser 379 Thr 380 Thr 384 Leu 386 Ala 388 Lys 389 Ile 390 Pro 392 Pro 394 Thr 399

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M4

Ser 435 Met 435 Leu 435 Ser 432 Glu 434 Lys 431 Glu 430 Met 429 Thr 428 Asp 427 Lys 426 Ser 425 Leu 424 Asp 401 Lys 402 Tyr 403 Ala 404 Arg 405 Ile 406 Leu 407 Phe 408 Pro 409 Val 410 Thr 411 Phe 412 Gly 413 Ala 414 Phe 415 Asn 416 Met 417 Val 418 Tyr 419 Trp 420 Val 421 Val 422 Tyr 423

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Alignment