GABAA subunit a2

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

GABAA a2 -- GENBANK

GABAAa2 - FASTA

GABAA a2 -- Alignment

 

 

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Asn 1 Ile 2 Gln 3 Glu 4 Leu 33 Gly 32 Arg 28 Leu 29 Arg 30 Asn 27 Asp 26 Tyr 25 Gly 24 Asp 23 Leu 22 Leu 21 Arg 20 Ala 7 Glu 6 Asp 5 Lys 8 Asn 9 Asn 10 Ile 11 Thr 12 Ile 13 Phe 14 Thr 15 Asn 16 Asp 19 Pro 31 Ile 17 Asp 35 Gly 34 Leu 18 Ser 36 Ile 37 Thr 38 Glu 39 Val 40 Phe 41 Thr 42 Asn 43 Ile 44 Tyr 45 Val 46 Thr 47 Ser 48 Phe 49 Gly 50 Pro 51 Val 52 Ser 53 Asp 54 Thr 55 Asp 56 Met 57 Val 63 Glu 58 Tyr 59 Thr 60 Ile 61 Asp 62 Phe 64 Phe 65 Arg 66 Gln 67 Lys 68 Trp 69 Leu 88 Asn 87 Asn 86 Leu 85 Arg 84 Leu 83 Ile 82 Asn 81 Met 80 Pro 79 Gly 78 Lys 77 Phe 76 Lys 75 Leu 74 Arg 73 Glu 72 Asp 71 Lys 70 Met 89 Ala 90 Ser 91 Lys 92 Ile 93 Trp 94 Thr 95 Pro 96 Asp 97 Thr 98 Phe 99 Phe 100 His 101 Asn 102 Gly 103 Lys 104 Lys 105 Ser 106 Val 107 Ala 108 His 109 Glu 137 Ala 136 Gln 135 Val 134 Thr 133 Leu 132 Arg 131 Met 130 Thr 129 Tyr 128 Leu 127 Asn 110 Met 111 Thr 112 Met 113 Pro 114 Asn 115 Lys 116 Leu 117 Leu 118 Arg 119 Ile 120 Gln 121 Asp 122 Asp 123 Gly 124 Thr 125 Leu 126 Asp 148 Met 147 Pro 146 Phe 145 Asp 144 Glu 143 Leu 142 His 141 Met 140 Pro 139 Cys 138 Lys 155 Phe 156 Pro 153 Leu 154 Ser 151 Cys 152 Ala 149 His 150 Ile 169 Tyr 168 Thr 167 Val 166 Phe 165 Ser 164 Thr 163 Thr 162 Tyr 161 Ala 160 Tyr 159 Gly 157 Ser 158 Gln 195 Gly 194 Leu 193 Leu 192 Asp 191 Tyr 190 Gln 189 Asn 188 Leu 187 Arg 186 Ser 185 Gly 184 Asp 183 Pro 182 Ala 181 Val 180 Gln 179 Val 178 Ser 177 Asp 176 Ser 175 Ala 174 Asn 173 Tyr 172 Thr 171 Trp 170 Val 211 Thr 210 Tyr 209 Glu 208 Gly 207 Thr 206 Ser 196 Ile 197 Gly 198 Lys 199 Glu 200 Thr 201 Ile 202 Lys 203 Ser 204 Ser 205 Met 212 Thr 213 Ala 214 His 215 Phe 216 His 217 Leu 218 Lys 219 Arg 220 Lys 221 Ile 222 Gly 223

 

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M1

Leu 246 Tyr 224 Phe 225 Val 226 Ile 227 Gln 228 Thr 229 Tyr 230 Leu 231 Pro 232 Cys 233 Ile 234 Met 235 Thr 236 Val 237 Thr 238 Leu 239 Ser 240 Gln 241 Val 242 Ser 243 Phe 244 Trp 245

 

 

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M1-M2 Linker

 

 

Asn 247 Arg 248 Glu 249 Ser 250

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M2

Ser 272 Val 251 Pro 252 Ala 253 Arg 254 Thr 255 Val 256 Phe 257 Gly 258 Val 259 Thr 260 Thr 261 Val 262 Leu 263 Thr 264 Met 265 Thr 267 Thr 268 Leu 269 Ser 270 Ile 271 Ala 273

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M2-M3 Linker

 

Ala 281 Val 280 Lys 279 Pro 278 Leu 277 Ser 276 Asn 275 Arg 274 Tyr 282 Ala 283 Thr 284

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M3

Val 307 Ala 285 Met 286 Asp 287 Thr 306 Trp 288 Phe 289 Ile 290 Ala 291 Val 292 Cys 293 Tyr 294 Ala 295 Phe 296 Val 297 Phe 298 Ser 299 Ala 300 Leu 301 Ile 302 Glu 303 Phe 304 Ala 305

 

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M3-M4 Linker

Asn 308 Gly 319 Tyr 309 Phe 310 Thr 311 Lys 312 Arg 313 Gly 314 Trp 315 Thr 316 Trp 317 Asp 318 Lys 320 Ser 321 Val 322 Val 323 Asn 324 Asp 325 Lys 326 Lys 327 Lys 328 Gly 329 Lys 330 Ala 331 Ser 332 Val 333 Met 334 Ile 335 Gln 336 Asn 337 Asn 338 Ala 339 Tyr 340 Ala 341 Val 342 Ala 343 Val 344 Ala 345 Asn 346 Tyr 347 Ala 348 Pro 349 Asn 350 Leu 351 Ser 352 Lys 353 Asp 354 Pro 355 Val 356 Leu 357 Ser 358 Thr 359 Ile 360 Ser 361 Lys 362 Ser 363 Ala 364 Thr 365 Tyr 366 Pro 367 Glu 368 Pro 369 Asn 370 Lys 371 Lys 372 Pro 373 Arg 392 Asp 391 Ile 390 Glu 374 Asn 375 Lys 376 Pro 377 Ala 378 Glu 379 Ala 380 Lys 381 Lys 382 Thr 383 Phe 384 Asn 385 Ser 386 Val 387 Ser 388 Lys 389

 

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M4

Pro 424 Ser 423 Val 422 Gly 421 Leu 420 Val 419 Arg 416 Glu 417 Met 393 Ser 394 Arg 395 Ile 396 Val 397 Phe 398 Pro 399 Val 400 Leu 401 Phe 402 Gly 403 Thr 404 Phe 405 Asn 406 Leu 407 Val 408 Tyr 409 Trp 410 Ala 411 Thr 412 Tyr 413 Leu 414 Asn 415 Pro 418

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Alignment