Human 5-HT3A -- Arg 426

Species Original Mutated to Mutation
Human Arg 426 Ser

R426S

Rat Equivalent Arg 425    
Mouse Equivalent Arg 431    

 

hArg426Ser

This mutation had little effect on the single-channel conductance.

Kelley SP, Dunlop JI, Kirkness EF, Lambert JJ, Peters JA (2003) A Cytoplasmic Region Determines Single-Channel Conductance in 5-HT3 Receptors. Nature 424(6946):321-324

 

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