Human 5-HT3A -- Arg 426

Species Original Mutated to Mutation
Human Arg 426 Ser


Rat Equivalent Arg 425    
Mouse Equivalent Arg 431    



This mutation had little effect on the single-channel conductance.

Kelley SP, Dunlop JI, Kirkness EF, Lambert JJ, Peters JA (2003) A Cytoplasmic Region Determines Single-Channel Conductance in 5-HT3 Receptors. Nature 424(6946):321-324


back to top
go back to 5-HT3A

Previous Next