Human 5-HT3A -- Pro 51
|Rat Equivalent||Pro 50|
|Mouse Equivalent||Pro 56||Ala||P56A|
Mutation resulted in the ablation of specific binding. No labeling was observed when their localization was studied using an antiserum specific for the N terminus of the 5-HT3A.
Deane CM, Lummis SCR (2001) The Role and Predicted Propensity of Conserved Proline Residues in the 5-HT3 Receptor. The Journal of Biological Chemistry 276(41):37962-37966
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