Human 5-HT3A -- Pro 118

Species Original Mutated to Mutation
Human Pro 118  

 

Rat Equivalent Pro 117    
Mouse Equivalent Pro 123 Ala P123A

 

mPro123Ala

No specific binding was observed. Labeling was observed using an antibody specific for the N terminus of the 5-HT3A subunit only in permeabilized cells.

Deane CM, Lummis SCR (2001) The Role and Predicted Propensity of Conserved Proline Residues in the 5-HT3 Receptor. The Journal of Biological Chemistry 276(41):37962-37966

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